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Some individuals may experience intellectual disability, [3] and females carrying a single copy of the mutated gene may show mild symptoms. [ 3 ] Duchenne muscular dystrophy is caused by mutations or deletions in any of the 79 exons encoding the large dystrophin protein , which is essential for maintaining the muscle fibers' cell membrane ...
Medically unexplained physical symptoms (MUPS or MUS) are symptoms for which a treating physician or other healthcare providers have found no medical cause, or whose cause remains contested. [1] In its strictest sense, the term simply means that the cause for the symptoms is unknown or disputed—there is no scientific consensus .
Dystonia is often intensified or exacerbated by physical activity, and symptoms may progress into adjacent muscles. [ 4 ] The disorder may be hereditary or caused by other factors such as birth-related or other physical trauma , infection , poisoning (e.g., lead poisoning ) or reaction to pharmaceutical drugs , particularly neuroleptics , [ 3 ...
Other symptoms include headaches, the inability to feel changes in the temperature, sweating, sexual dysfunction, and loss of bowel and bladder control. It is usually seen in the cervical region but can extend into the medulla oblongata and pons or it can reach downward into the thoracic or lumbar segments.
Signs and symptoms are also applied to physiological states outside the context of disease, as for example when referring to the signs and symptoms of pregnancy, or the symptoms of dehydration. Sometimes a disease may be present without showing any signs or symptoms when it is known as being asymptomatic . [ 13 ]
The Abnormal Involuntary Movement Scale (AIMS) examination is a test used to identify the symptoms of tardive dyskinesia (TD). The test is not meant to tell whether there is an absence or presence of tardive dyskinesia. It just scales to the level of symptoms indicated by the actions observed. The levels range from none to severe.
Myoclonus is a brief, involuntary, irregular (lacking rhythm) twitching of a muscle, a joint, or a group of muscles, different from clonus, which is rhythmic or regular.. Myoclonus (myo-"muscle", clonus "spasm") describes a medical sign and, generally, is not a diagnosis of a dis
Chronic pain and PTSD can also be "mutually maintaining", with cognitive, behavioural, and affective patterns creating a cycle of worsening physical and mental symptoms. [36] Under this model, depressive symptoms (such as reduced activity and increased physiological arousal) aggravate pain symptoms, and unhealthy coping strategies (such as ...