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Estradiol level with a single 100 µg/day estradiol reservoir patch (Estraderm) with and without ethanol added in postmenopausal women. [9] [10] This patch has a 3- to 4-day duration and is designed for twice-weekly application. In one group, ethanol was injected into the area between the patch and the skin on day 3.
Bee venom is a complex mixture of proteins and smaller molecules. The main component is melittin , which amounts to 52% of venom peptides [ 2 ] One of the main allergens is phospholipase A 2 , which amounts to 12% and is an enzyme that catalyzes the hydrolysis of phospholipids , causing degradation of cell membranes . [ 3 ]
Bee stings differ from insect bites, with the venom of stinging insects having considerable chemical variation. The reaction of a person to a bee sting may vary according to the bee species. While bee stinger venom is slightly acidic and causes only mild pain in most people, [1] allergic reactions may occur in people with allergies to venom ...
The duration of the pain of insect stings categorized into Pain Level 1 generally is five minutes or less. [2] Many small bees are categorized into a pain level of 1, with their venom containing polypeptides such as melittin, apamin, and MCD peptide. Melittin is the main toxin of bee venom, and it damages red blood cells and white blood cells.
Apitherapy is a branch of alternative medicine that uses honey bee products, including honey, pollen, propolis, royal jelly and bee venom. There has been no scientific or clinical evidence for the efficacy or safety of apitherapy treatments. [1] [2] Bee venom can cause minor or major reactions, including allergic responses, anaphylaxis or death.
The title page of Beck's Bee Venom Therapy, 1935. Bodog Felix Beck (6 August 1868 – 1 January 1942) was a Hungarian-born American physician who specialized in the treatment of arthritic and rheumatoid conditions using bee venom and who coined the term "bee venom therapy". There are no studies proving the ability of bee venom to cure any ailment.
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