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Therefore, it is responsible for CRL deneddylation – at the same time, it is able to bind denedyllated cullin-RING complex and retain them in deactivated form. COP9 signalosome thus serves as a sole deactivator of CRLs. [1] The complex was originally identified in plants, [2] [3] and subsequently found in all eukaryotic organisms including human.
10987 26754 Ensembl ENSG00000121022 ENSMUSG00000025917 UniProt Q92905 O35864 RefSeq (mRNA) NM_006837 NM_001277101 NM_013715 RefSeq (protein) NP_006828 NP_006828.2 NP_001264030 NP_038743 Location (UCSC) Chr 8: 67.04 – 67.08 Mb Chr 1: 10.09 – 10.11 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 ...
The United Nations Climate Change Conferences are yearly conferences held in the framework of the United Nations Framework Convention on Climate Change (UNFCCC). They serve as the formal meeting of the UNFCCC parties – the Conference of the Parties (COP) – to assess progress in dealing with climate change, and beginning in the mid-1990s, to negotiate the Kyoto Protocol to establish legally ...
The conference included the 9th Conference of the Parties (COP9) to the United Nations Framework Convention on Climate Change (UNFCCC). The parties agreed to use the Adaptation Fund established at COP7 in 2001 primarily in supporting developing countries better adapt to climate change. The fund would also be used for capacity-building through ...
Created Date: 8/30/2012 4:52:52 PM
COP9 signalosome: Catalyses the hydrolysis of NEDD8 protein from the Cullin subunit of Cullin-RING ubiquitin ligases (CRL). Therefore, it is responsible for CRL deneddylation – at the same time, it is able to bind deneddylated cullin-RING complex and retain them in deactivated form. COP9 signalosome thus serves as a sole deactivator of CRLs. [11]
Addendum. Part two: Action taken by the Conference of the Parties at its first session (PDF), Geneva, Switzerland: United Nations Office [permanent dead link ]. Available as a PDF in the official UN languages. COP (14 March 2008), Report of the Conference of the Parties (COP) on its thirteenth session, held in Bali from 3 to 15 December 2007 ...
64708 26895 Ensembl ENSG00000144524 n/a UniProt Q9H9Q2 Q8BV13 RefSeq (mRNA) NM_001282949 NM_001282950 NM_001282951 NM_001282952 NM_001308381 NM_022730 NM_001369483 NM_172974 NM_001360887 NM_001360888 RefSeq (protein) NP_001269878 NP_001269879 NP_001269880 NP_001269881 NP_001295310 NP_073567 NP_001356412 NP_766562 NP_001347816 NP_001347817 Location (UCSC) Chr 2: 231.78 – 231.81 Mb n/a PubMed ...