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Sertraline is highly plasma protein bound (98.5%) across a concentration range of 20 to 500 ng/mL. [5] Despite the high plasma protein binding, sertraline and its metabolite desmethylsertraline at respective tested concentrations of 300 ng/mL and 200 ng/mL were found not to interfere with the plasma protein binding of warfarin and propranolol ...
The first reported evidence of stimulant medication used to treat children with concentration and hyperactivity problems came in 1937. [223] Charles Bradley in Providence, Rhode Island, reported that a group of children with behavioral problems improved after being treated with the stimulant Benzedrine.
Sertraline has about 60 times more potent inhibition potential on 5-HT than either NE or DA re-uptake. It is possible that only modest inhibition of DAT and NET is needed to cause an increase in energy, motivation and concentration, specially when added to other activity such as SERT inhibition. [18]
In children, SSRIs can be considered a second line therapy in those with moderate-to-severe impairment, with close monitoring for psychiatric adverse effects. [28] SSRIs, especially fluvoxamine , which is the first one to be FDA approved for OCD, are efficacious in its treatment; patients treated with SSRIs are about twice as likely to respond ...
This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress.. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication.
Zoloft – an antidepressant of the SSRI class; Zonegran (zonisamide) – an anticonvulsant used to treat other seizures; Zulresso (brexanolone) – a GABA modulator antidepressant; Zyban (bupropion) – same active ingredient as Wellbutrin, but marketed as a smoking cessation aid
[20] [55] For children and adolescents with moderate-to-severe depressive disorder, fluoxetine seems to be the best treatment (either with or without cognitive behavioural therapy) but more research is needed to be certain. [43] [44] [56] [55] Sertraline, escitalopram, duloxetine might also help in reducing symptoms. [55]
ASD-002 - a child-specific (non-acidic, sustained-release) anti-hyper excitatory ester prodrug of the potassium channel modulator NSAID mefenamic acid (MFA, approved as Ponstel) [24] to prevent toddlers from becoming non-verbal (developmental language disorder, DLD) Bryostatin-1 (MW-904) – protein kinase C stimulant [25]