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A micrograph showing yolk sac tumour, with smooth external surface and capsule tears [citation needed] The ovarian yolk sac tumors, also known as endodermal sinus tumors, are accountable for approximately 15.5% of all OGCTs. [8] They have been observed in women particularly in their early ages, and rarely after 40 years of age. [9]
Histologically, yolk sac tumors are characterized by the presence of Schiller-Duval bodies (which are pathognomonic for yolk sac tumors) and a reticular pattern. Yolk sac tumors commonly secrete alpha-fetoprotein and can be immunohistochemically stained for its presence; the level of alpha-fetoprotein in the blood is a useful marker of ...
Ovarian germ cell tumors: Benign [39] Dysgerminoma: Typically occurs in young women between the ages of 10–30 years of age [40] Choriocarcinoma: Can occur without gynecological symptoms [41] Yolk sac tumor: Malignant. Occurs in young children [42] Teratoma: Very rare. Often occurs in newborns [medical citation needed] Ovarian serous ...
Tumor of the ovary vary remarkably as they may arise from any of the 3 cell types of the normal ovary. Ovarian tumors are classified according to the histology of the tumor, obtained in a pathology report. Histology dictates many aspects of clinical treatment, management, and prognosis. The most common forms are:
Polyembryoma is a rare, very aggressive form of germ cell tumor usually found in the ovaries. Polyembryoma has features of both yolk sac tumour and undifferentiated teratoma/embryonal carcinoma, with a characteristic finding of embryoid bodies lying in a loose mesenchymal stroma. It has been found in association with Klinefelter syndrome. [1]
A dysgerminoma is a type of germ cell tumor; [1] it usually is malignant and usually occurs in the ovary.. A tumor of the identical histology but not occurring in the ovary may be described by an alternate name: seminoma in the testis [2] or germinoma in the central nervous system or other parts of the body.
The 1997 International Germ Cell Consensus Classification [17] is a tool for estimating the risk of relapse after treatment of malignant germ-cell tumor. A small study of ovarian tumors in girls [18] reports a correlation between cystic and benign tumors, and conversely, solid and malignant tumors. Because the cystic extent of a tumor can be ...
The term "germinoma" most often refers to a tumor in the brain that has a histology identical to two other tumors, dysgerminoma in the ovary and seminoma in the testis. [3] Since 1994, MeSH has defined germinoma as "a malignant neoplasm of the germinal tissue of the gonads , mediastinum , or pineal region" [ 4 ] and within its scope included ...