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Goblet cells are simple columnar epithelial cells, having a height of four times that of their width. The cytoplasm of goblet cells tends to be displaced toward the basal end of the cell body by the large mucin granules, which accumulate near the apical surface of the cell along the Golgi apparatus, which lies between the granules and the nucleus.
The epithelium, the most exposed part of the mucosa, is a glandular epithelium with many goblet cells. Goblet cells secrete mucus , which lubricates the passage of food along and protects the intestinal wall from digestive enzymes.
During each mitosis, one of the two daughter cells remains in the crypt as a stem cell, while the other differentiates and migrates up the side of the crypt and eventually into the villus. These stem cells can differentiate into either an absorptive (enterocytes) or secretory (Goblet cells, Paneth cells, enteroendocrine cells) lineages. [3]
MUC5B is a polymeric protein secreted from submucosal glands and some goblet cells, and this is in the form of strands. [9] [10] In the airways—the trachea, bronchi, and bronchioles—the lining of mucus is produced by specialized airway epithelial cells called goblet cells, and submucosal glands.
Most are multicellular, but goblet cells are single-celled glands. ... Anatomy Atlases – Microscopic Anatomy, plate 10.182 - "Lingual glands" Overview at siumed.edu
The epithelium contains goblet cells, which are glandular, column-shaped cells that produce mucins, the main component of mucus. Mucus helps to moisten and protect the airways. [ 7 ] Mucus lines the ciliated cells of the trachea to trap inhaled foreign particles that the cilia then waft upward toward the larynx and then the pharynx where it can ...
The epithelium that forms the innermost part of the mucosa has five distinct types of cells that serve different purposes: enterocytes with microvilli, which digest and absorb nutrients; goblet cells, which secrete mucin, a substance that lubricates the wall of the organ; Paneth cells, most common in the terminal part of the ileum, are only ...
A gland is a cell or an organ in an animal's body that produces and secretes different substances that the organism needs, either into the bloodstream or into a body cavity or outer surface. [1] A gland may also function to remove unwanted substances such as urine from the body. [2] There are two types of gland, each with a different method of ...