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However, Dr. Pongpirul points out that the study used a lower but “more natural” dose of turmeric powder vs. higher-dose curcumin supplements that are commonly available in the U.S ...
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Curcumin, which shows positive results in most drug discovery assays, is regarded as a false lead that medicinal chemists include among "pan-assay interference compounds". This attracts undue experimental attention while failing to advance as viable therapeutic or drug leads, [ 3 ] [ 6 ] [ 17 ] although some derivatives of curcumin such as EF ...
Some chemicals found in trace amounts in food, as well as some dietary supplements, have been shown to inhibit 5-LOX; these include baicalein, caffeic acid, curcumin, [3] hyperforin and St John's wort. [8] [9] [10]
Even more impressive is a 1999 study from Phytotherapy Research that found that the anti-inflammatory action of curcumin rivals that of pharmaceutical drugs recommended for the same purpose.
There has been interest in the drug for the potential treatment of prostate cancer as well. [2] [3] As of 2017, it is in phase II clinical trials for acne vulgaris. [1] Dimethylcurcumin is an androgen receptor (AR) inhibitor and shows strong and specific antiandrogenic activity in vitro (e.g., against LNCaP cell growth) at sufficiently high ...
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