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This has a cost of about 2 to 3 cents per person per treatment. [1] This is known as mass drug administration and is often carried out among school-age children. [32] For this purpose, broad-spectrum benzimidazoles such as mebendazole and albendazole are the drugs of choice recommended by WHO. [33]
Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. [5] This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections and hydatid disease, among others. [5] It has been used for treatment of giardiasis but is not a preferred agent.
Levamisole may be quantified in blood, plasma, or urine as a diagnostic tool in clinical poisoning situations or to aid in the medicolegal investigation of suspicious deaths involving adulterated street drugs. About 3% of an oral dose is eliminated unchanged in the 24-hour urine of humans.
Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
Other drugs that can be effective are albendazole and thiabendazole (25 mg/kg twice daily for 5 days—400 mg maximum (generally)). [11] All patients who are at risk of disseminated strongyloidiasis should be treated. The optimal duration of treatment for patients with disseminated infections is not clear. [10]
When a 64-year-old Australian woman was sent to hospital for brain surgery, neurosurgeon Dr. Hari Priya Bandi was not expecting to pull out a live 8-centimeter (3-inch) long parasitic roundworm ...
The roundworm, Dracunculus has a complex mode of transmission: it is acquired from drinking infested water or eating frogs and fish that contain (had eaten) infected crustaceans ; and can also be transmitted from infected pets (cats and dogs). [30] Roundworms such as Brugia, Wuchereria and Onchocerca are directly transmitted by mosquitoes.
A. lumbricoides is the largest intestinal roundworm and is the most common helminth infection of humans worldwide. Infestation can cause morbidity by compromising nutritional status, [ 3 ] affecting cognitive processes, [ 4 ] inducing tissue reactions such as granuloma to larval stages, and by causing intestinal obstruction , which can be fatal.