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  2. Lipid peroxidation - Wikipedia

    en.wikipedia.org/wiki/Lipid_peroxidation

    Lipid peroxidation, or lipid oxidation, is a complex chemical process that leads to oxidative degradation of lipids, [1] resulting in the formation of peroxide and hydroperoxide derivatives. [2] It occurs when free radicals , specifically reactive oxygen species (ROS), interact with lipids within cell membranes , typically polyunsaturated fatty ...

  3. Chain reactions in living organisms - Wikipedia

    en.wikipedia.org/wiki/Chain_reactions_in_living...

    Chain reaction in chemistry and physics is a process that produces products capable of initiating subsequent processes of a similar nature. It is a self-sustaining sequence in which the resulting products continue to propagate further reactions. [1] Examples of chain reactions in living organisms are lipid peroxidation in cell membranes [2] and ...

  4. Isotope effect on lipid peroxidation - Wikipedia

    en.wikipedia.org/wiki/Isotope_effect_on_lipid...

    Mechanism of isotope effect on lipid peroxidation. An animated model of a chain reaction with slow, oxidation-resistant elements. PUFAs are highly prone to oxidative damage through a purely chemical, non-enzymatic chain reaction. With tight packaging of PUFAs in membranes, the oxidation of a single PUFA molecule rapidly leads to a chain ...

  5. Oxidative stress - Wikipedia

    en.wikipedia.org/wiki/Oxidative_stress

    These metals are thought to induce Fenton reactions and the Haber-Weiss reaction, in which hydroxyl radical is generated from hydrogen peroxide. [76] The hydroxyl radical then can modify amino acids. For example, meta-tyrosine and ortho-tyrosine form by hydroxylation of phenylalanine. Other reactions include lipid peroxidation and oxidation of ...

  6. Reactive oxygen species - Wikipedia

    en.wikipedia.org/wiki/Reactive_oxygen_species

    Specific examples include stroke and heart attack. [citation needed] In general, the harmful effects of reactive oxygen species on the cell are the damage of DNA or RNA, oxidation of polyunsaturated fatty acids in lipids (lipid peroxidation), oxidation of amino acids in proteins, and oxidative deactivation of specific enzymes by oxidation co ...

  7. Unsaturated fat - Wikipedia

    en.wikipedia.org/wiki/Unsaturated_fat

    An unsaturated fat is a fat or fatty acid in which there is at least one double bond within the fatty acid chain. A fatty acid chain is monounsaturated if it contains one double bond, and polyunsaturated if it contains more than one double bond. A saturated fat has no carbon-to-carbon double bonds, so the maximum possible number of hydrogen is ...

  8. 4-Hydroxynonenal - Wikipedia

    en.wikipedia.org/wiki/4-Hydroxynonenal

    Infobox references. 4-Hydroxynonenal, or 4-hydroxy-2E-nonenal or 4-hydroxy-2-nonenal or 4-HNE or HNE, (C 9 H 16 O 2), is an α,β-unsaturated hydroxyalkenal that is produced by lipid peroxidation in cells. 4-HNE is the primary α,β-unsaturated hydroxyalkenal formed in this process. It is a colorless oil.

  9. Lipofuscin - Wikipedia

    en.wikipedia.org/wiki/Lipofuscin

    Lipofuscin. Lipofuscin is the name given to fine yellow-brown pigment granules composed of lipid -containing residues of lysosomal digestion. [1][2] It is considered to be one of the aging or "wear-and-tear" pigments, found in the liver, kidney, heart muscle, retina, adrenals, nerve cells, and ganglion cells. [3]