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Topical antifungal drugs are used to treat fungal infections on the skin, scalp, nails, vagina or inside the mouth. These medications come as creams, gels, lotions, ointments, powders, shampoos, tinctures and sprays. Most antifungal drugs induce fungal cell death by destroying the cell wall of the fungus.
Some fungi (e.g. Candida krusei and fluconazole) exhibit intrinsic resistance to certain antifungal drugs or classes, whereas some species develop antifungal resistance to external pressures. Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical antifungals ...
Medicinal fungi are fungi that contain metabolites or can be induced to produce metabolites through biotechnology to develop prescription drugs. Compounds successfully developed into drugs or under research include antibiotics , anti-cancer drugs , cholesterol and ergosterol synthesis inhibitors, psychotropic drugs, immunosuppressants and ...
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases, such as those caused by helminths, [1] amoeba, [2] ectoparasites, parasitic fungi, [3] and protozoa, [1] among others.
Tinea is a very common fungal infection of the skin. Tinea is often called "ringworm" because the rash is circular, with a ring-like appearance. It is sometimes equated with dermatophytosis , and, while most conditions identified as "tinea" are members of the imperfect fungi that make up the dermatophytes , conditions such as tinea nigra and ...
According to the WHO, the most dangerous fungi include candida auris, aspergillus, and cryptococcus. 4 of the most dangerous fungi that can make you sick, according to the WHO — from toxic mold ...
The World Health Organization has drawn up the first ever list of fungal pathogens posing the greatest threat to human health, warning that some strains are increasingly drug-resistant and ...
The rising fungal resistance to fluconazole and related azole drugs spurs the need to find effective combative solutions swiftly. Rising resistance raises concerns since fluconazole is commonly used due to its inexpensiveness and ease of administration, according to the World Health Organization.