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Phossy jaw, formally known as phosphorus necrosis of the jaw, was an occupational disease affecting those who worked with white phosphorus (also known as yellow phosphorus) without proper safeguards. It is also likely to occur as the result of use of chemical weapons that contain white phosphorus.
Phossy jaw developed by inhalation of phosphorus vapour—particularly when the ingredient was heated—which caused osteonecrosis of the jaw bone. [13] This manifested itself in, initially, toothaches and flu-like symptoms, then tooth loss, abscesses, swelling of the gums, the formation of fistula and necrosis of the jaw. [ 14 ]
Osteonecrosis of the jaw (ONJ) is a severe bone disease (osteonecrosis) that affects the jaws (the maxilla and the mandible). Various forms of ONJ have been described since 1861, and a number of causes have been suggested in the literature.
Although the methods of action are not yet completely understood, it is hypothesized that medication-associated osteonecrosis of the jaw is related to a defect in jaw bone healing and remodelling. The inhibition of osteoclast differentiation and function, precipitated by drug therapy, leads to decreased bone resorption and remodelling.
A nurse with a titanium jaw and a myriad of rare medical conditions is set to run the Oxford Half to inspire those going through something similar to not “give up hope”.
The background to the treaty was the extensive medical problems such as phossy jaw facing workers in match production. The treaty was concluded on 26 September 1906. It entered into force on 1 January 1912. The Convention remains in force for 48 states. Switzerland is the depositary for the treaty.
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Radium jaw, or radium necrosis, is a historic occupational disease brought on by the ingestion and subsequent absorption of radium into the bones of radium dial painters. [ 1 ] [ 2 ] It also affected those consuming radium-laden patent medicines .