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Phossy jaw, formally known as phosphorus necrosis of the jaw, was an occupational disease affecting those who worked with white phosphorus (also known as yellow phosphorus) without proper safeguards. It is also likely to occur as the result of use of chemical weapons that contain white phosphorus.
Although the methods of action are not yet completely understood, it is hypothesized that medication-associated osteonecrosis of the jaw is related to a defect in jaw bone healing and remodelling. The inhibition of osteoclast differentiation and function, precipitated by drug therapy, leads to decreased bone resorption and remodelling.
Osteonecrosis of the jaw (ONJ) is a severe bone disease (osteonecrosis) that affects the jaws (the maxilla and the mandible). Various forms of ONJ have been described since 1861, and a number of causes have been suggested in the literature.
Toni Bull has the nickname Titanium Toni after having two titanium jaw joints fitted.
Radium jaw, or radium necrosis, is a historic occupational disease brought on by the ingestion and subsequent absorption of radium into the bones of radium dial painters. [ 1 ] [ 2 ] It also affected those consuming radium-laden patent medicines .
Phossy jaw developed by inhalation of phosphorus vapour—particularly when the ingredient was heated—which caused osteonecrosis of the jaw bone. [13] This manifested itself in, initially, toothaches and flu-like symptoms, then tooth loss, abscesses, swelling of the gums, the formation of fistula and necrosis of the jaw. [ 14 ]
For years, I told consumers who ran into problems with their auto loans, mortgages, credit cards, payment apps, student loan servicers, credit reports and more to reach out to the Consumer ...
It damages the liver, kidneys, and other organs before eventually being metabolized to non-toxic phosphate. Chronic low-level exposure leads to tooth loss and phossy jaw which appears to be caused by the formation of amino bisphosphonates. [10] [14] [15] White phosphorus is used as a weapon because it is pyrophoric. For the same reasons, it is ...