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The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
The causes of schizophrenia may include genetic and environmental factors. [7] Genetic factors include a variety of common and rare genetic variants . [ 21 ] Possible environmental factors include being raised in a city , childhood adversity, cannabis use during adolescence, infections, the age of a person's mother or father , and poor ...
In alternative medicine, some practitioners believe that there is a vast number of physical causes for the diagnosis of schizophrenia. [196] While some of these explanations may stretch credulity, others (such as heavy metal poisoning and nutritional imbalances) have been supported at least somewhat by research. [47] [197] [198]
'This will turn out to be the most important break in the disease,' the Broad Institute's director Eric Lander said.
Provided the behaviour is presenting no problems to the individual or to other people, then there is no need to regard the behaviour as a mental disorder. Those who support the psychodynamic model, however, claim the behavioural model focuses only on symptoms and ignores the causes of abnormal behaviour.
Risk factors for mental illness include psychological trauma, adverse childhood experiences, genetic predisposition, and personality traits. [7] [8] Correlations between mental disorders and substance use are also found to have a two way relationship, in that substance use can lead to the development of mental disorders and having mental disorders can lead to substance use/abuse.
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