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Joseph Carey Merrick (5 August 1862 – 11 April 1890) was an English artist known for his severe physical deformities. He was first exhibited at a freak show under the stage name "The Elephant Man", and then went to live at the London Hospital, in Whitechapel, after meeting Sir Frederick Treves, subsequently becoming well known in London society.
Proteus syndrome is a rare disorder with a genetic background [1] that can cause tissue overgrowth involving all three embryonic lineages. Patients with Proteus syndrome tend to have an increased risk of embryonic tumor development. [2] The clinical and radiographic symptoms of Proteus syndrome are highly variable, as are its orthopedic ...
Doctors were unable to provide a diagnosis for many years, until some doctors decided on Proteus syndrome in May 2006, [1] though Sellar's condition is atypical in many respects. The most famous person with Proteus syndrome may be Joseph Merrick, the "Elephant Man". There is no known cure. [1]
Proteus syndrome, a very rare congenital disorder known mostly for its most famous sufferer Joseph Merrick (the Elephant Man) Proteus-like syndrome , a condition similar to Proteus syndrome, but with an uncertain etiology
Proteus syndrome, a genetic disorder best known as the condition possibly experienced by Joseph Merrick, the so-called Elephant Man [citation needed] Other causes may include the following: Repeated streptococcal infection [2] Lymphadenectomy [2] Hereditary birth defects [2] Pretibial myxedema
Since 2003, Hurt was a patron of the Proteus Syndrome Foundation, both in the United Kingdom and in the US. [61] Proteus syndrome is the condition that Joseph Merrick, who Hurt played (renamed as John Merrick) in The Elephant Man, is thought to have suffered from, although Merrick's exact condition is still not known with certainty. [62] [63 ...
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The article on Joseph Merrick reads: "During 2003, DNA tests conducted by Dr. Charis Eng on samples of Merrick's hair and bone showed no mutation in the PTEN gene (only present in some Proteus syndrome sufferers). Hence, there is as of yet, no physical evidence to support the theory that Merrick suffered from Proteus syndrome."