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Viruses that contain double-stranded DNA (dsDNA) share the same kind of genetic material as all organisms, and can therefore use the replication enzymes in the host cell nucleus to replicate the viral genome. Many RNA viruses typically replicate in the cytosol, and can directly access the host cell's ribosomes to manufacture viral proteins once ...
Viruses of the flaviviridae Family, such as hepatitis C virus, have developed complex viral mechanisms to rearrange the cell membrane, creating a membranaceous web designed to house viral replication machinery. These viruses utilize endogenous host cell nuclear pore complex proteins to shield viral RNA from Pattern Recognition Receptors by ...
Some viruses can "hide" within a cell, which may mean that they evade the host cell defenses or immune system and may increase the long-term "success" of the virus. This hiding is deemed latency. During this time, the virus does not produce any progeny, it remains inactive until external stimuli—such as light or stress—prompts it to activate.
The genetic material within virus particles, and the method by which the material is replicated, varies considerably between different types of viruses. DNA viruses The genome replication of most DNA viruses takes place in the cell's nucleus. If the cell has the appropriate receptor on its surface, these viruses enter the cell either by direct ...
Negative-strand RNA viruses (−ssRNA viruses) are a group of related viruses that have negative-sense, single-stranded genomes made of ribonucleic acid (RNA). They have genomes that act as complementary strands from which messenger RNA (mRNA) is synthesized by the viral enzyme RNA-dependent RNA polymerase (RdRp). During replication of the ...
[1] [2] As they cannot replicate independently, they must infect cells and hijack the host's replication machinery in order to produce copies of themselves. [2] Viruses do this by inserting their genome—which can be DNA or RNA , either single-stranded or double-stranded —into the host. [ 3 ]
The healthy virome consists of three distinct components: (i) viruses that systematically enter the human organism, primarily, with food, but do not replicate in humans; (ii) viruses infecting prokaryotes and, possibly, unicellular eukaryotes that comprise the healthy human microbiome; and (iii) viruses that actually replicate and persist in ...
When a virus infects a cell, the virus forces it to make thousands more viruses. It does this by making the cell copy the virus's DNA or RNA, making viral proteins, which all assemble to form new virus particles. [37] There are six basic, overlapping stages in the life cycle of viruses in living cells: [38]