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The aim of the PRISMA statement is to help authors improve the reporting of systematic reviews and meta-analyses. [3] PRISMA has mainly focused on systematic reviews and meta-analysis of randomized trials, but it can also be used as a basis for reporting reviews of other types of research (e.g., diagnostic studies, observational studies).
The design of a study defines the study type (descriptive, correlational, semi-experimental, experimental, review, meta-analytic) and sub-type (e.g., descriptive-longitudinal case study), research problem, hypotheses, independent and dependent variables, experimental design, and, if applicable, data collection methods and a statistical analysis ...
Research synthesis or evidence synthesis is the process of combining the results of multiple primary research studies aimed at testing the same conceptual hypothesis. It may be applied to either quantitative [1] or qualitative research. [2] Its general goals are to make the findings from multiple different studies more generalizable and ...
A meta-analysis of such expression profiles was performed to derive novel conclusions and to validate the known findings. [148] Meta-analysis of whole genome sequencing studies provides an attractive solution to the problem of collecting large sample sizes for discovering rare variants associated with complex phenotypes.
Gee's original software for performing jackknife and combinatorial meta analysis was based on older meta-analytic macros written in the SAS programming language. It was the basis of one report in the area of arthritis treatment. [2] While this software was shared with colleagues informally, it was not published.
A forest plot, also known as a blobbogram, is a graphical display of estimated results from a number of scientific studies addressing the same question, along with the overall results. [1] It was developed for use in medical research as a means of graphically representing a meta-analysis of the results of randomized controlled trials.
A meta-regression can be classified in the same way—meta-regression and network meta-regression—depending on the number of distinct treatments in the regression analysis. Meta-analysis (and meta-regression) is often placed at the top of the evidence hierarchy provided that the analysis consists of individual participant data of randomized ...
A systematic review is a scholarly synthesis of the evidence on a clearly presented topic using critical methods to identify, define and assess research on the topic. [1] A systematic review extracts and interprets data from published studies on the topic (in the scientific literature), then analyzes, describes, critically appraises and summarizes interpretations into a refined evidence-based ...