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Testosterone (T) is a medication and naturally occurring steroid hormone. [9] It is used to treat male hypogonadism, gender dysphoria, and certain types of breast cancer. [9] [10] It may also be used to increase athletic ability in the form of doping. [9] It is unclear if the use of testosterone for low levels due to aging is beneficial or ...
Testosterone can be taken by a variety of different routes of administration. [2] [3] These include oral, buccal, sublingual, intranasal, transdermal (gels, creams, patches, solutions), vaginal (creams, gels, suppositories), rectal (suppositories), by intramuscular or subcutaneous injection (in oil solutions or aqueous suspensions), and as a subcutaneous implant.
Testosterone isobutyrate is used in the treatment of hypogonadism in men and delayed puberty in adolescent boys. [1] It is also used in the treatment of Klinefelter's syndrome, aplastic anemia, Cushing's syndrome (as an anabolic to preserve lean body mass), postmenopausal osteoporosis in women, advanced breast cancer in women, breast pain in women, and cachexia. [1]
Buccal testosterone propionate tablets were introduced for medical use in the mid-to-late 1940s under the brand name Oreton Buccal Tablets. [21] [22] [23] An aqueous suspension of testosterone propionate was marketed by Ciba by 1950. [24]
Testosterone phenylacetate in aqueous suspension by intramuscular injection, similarly to other aqueous suspension formulations, causes local injection site reactions, including local pain, swelling, and tenderness. [11] These symptoms last for several days after the injection and then subside. [11]
In December 2009, Sports Illustrated named baseball's steroid scandal of performance-enhancing drugs as the number one sports story of the decade of the 2000s. [2] The current penalties, adopted on March 28, 2014, are 80 games for a first offense, 162 games for a second offense, and a permanent suspension ("lifetime ban") for a third. [3]
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