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Human genetic variants that likely cause dysregulation of critical meiotic processes have been identified in 14 female infertility associated genes. [53] A major cause of female infertility is premature ovarian insufficiency. [54] This insufficiency is a heterogeneous disease that affects about 1% of women who are under the age of 40. [54]
Female fertility agents are medications that improve female’s ability to conceive pregnancy. These agents are prescribed for infertile female who fails to conceive pregnancy after 1-year of regular and unprotected sexual intercourse. [1] The following will cover the advancements of female fertility agents, major causes of female infertility.
Male infertility is responsible for 20–30% of infertility cases, while 20–35% are due to female infertility, and 25–40% are due to combined problems in both partners. [29] [5] In 10–20% of cases, no cause is found. [5] The most common cause of female infertility are ovulation problems, usually manifested by scanty or absent menstrual ...
Nearly 10 percent of men ages 15 to 44 experience some form of infertility. An estimated 1 in 8 women ages 15 to 49 have received some infertility services in their lifetime.
Approximately 20% of female infertility can be attributed to tubal causes. [1] Distal tubal obstruction (affecting the distal tubal opening (towards the ovary)) is typically associated with hydrosalpinx formation and often caused by Chlamydia trachomatis. [1] Pelvic adhesions may be associated with such an infection.
Endometriosis is estimated to occur in 7% to 10% of women, with an associated risk of infertility for between 30% and 50% of this population. [ 1 ] [ 2 ] [ 3 ] Endometriosis is commonly classified under the revised American Society for Reproductive Medicine system from minimal endometriosis to severe endometriosis .
Chronic anovulation is a common cause of infertility. In addition to the alteration of menstrual periods and infertility, chronic anovulation can cause or exacerbate other long-term problems, such as hyperandrogenism or osteopenia. It plays a central role in the multiple imbalances and dysfunctions of polycystic ovary syndrome.
The $30 billion global fertility industry overwhelmingly caters to women—but that's changing. The global ‘spermpocalypse’ proves infertility is no longer just a women’s problem, says male ...