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One of the typical uses of additive effect is to detect synergy. [21] Additive effect can be considered as the baseline effect in methods of determining the presence of synergistic effect between two or more drugs. Synergistic effect is similar to additive effect. The only difference is it has a combination effect greater than additive effect.
In the synergistic response, the applied antibiotics work together to produce an effect more potent than if each antibiotic were applied singly. [1] Compare to the additive effect , where the potency of an antibiotic combination is roughly equal to the combined potencies of each antibiotic singly, and antagonistic effect, where the potency of ...
One way of quantifying synergy in human social groups is via energy use, where larger groups of humans (i.e., cities) use energy more efficiently that smaller groups of humans. [1] Human synergy can also occur on a smaller scale, like when individuals huddle together for warmth or in workplaces where labor specialization increase efficiencies. [38]
The Gaia hypothesis (/ ˈ ɡ aɪ. ə /), also known as the Gaia theory, Gaia paradigm, or the Gaia principle, proposes that living organisms interact with their inorganic surroundings on Earth to form a synergistic and self-regulating complex system that helps to maintain and perpetuate the conditions for life on the planet.
In the first one, first messenger cross through the cell membrane, binding and activating intracellular receptors localized at nucleus or cytosol, which then act as transcriptional factors regulating directly gene expression. This is possible due to the lipophilic nature of those ligands, mainly hormones.
A syndemic is a synergistic epidemic. The term was developed by Merrill Singer in the mid-1990s, culminating in a 2009 textbook. [7] Disease concentration, disease interaction, and their underlying social forces are the core concepts. [8]
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Rhizosphere microorganisms can influence one another, and the resulting consortia of PGPB + PGPB (e.g., a nitrogen-fixing bacterium such as Rhizobium spp. and Pseudomonas fluorescens), AMF + PGPB, and Trichoderma + PGPB may have synergetic effects on plant growth and fitness, providing the plant with enhanced benefits to overcome biotic and ...