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DCIS has been classified according to the architectural pattern of the cells (solid, cribriform, papillary, and micropapillary), tumor grade (high, intermediate, and low grade), or the presence or absence of comedo histology; [8] or, in the case of the apocrine cell-based in situ carcinoma, apocrine ductal carcinoma in situ, it may be ...
Many of them do not go on to become cancers—but a small percentage of so-called high grade DCIS do, and doctors only have crude ways to distinguish them. ... treatment for DCIS involved surgery ...
Comedocarcinoma is a kind of breast cancer that demonstrates comedonecrosis, which is the central necrosis [1] of cancer cells within involved ducts. Comedocarcinomas are usually non-infiltrating and intraductal tumors, characterized as a comedo-type, high-grade ductal carcinoma in situ (DCIS).
The sum of these grades is a number between 3 and 9. The score is called a Bloom Richardson Grade (BR) and is expressed [sum of the grades]/9. For example, cells that were graded 2 on all three parameters would result in a BR score of 6/9. A score of 5 and under is considered low. 6 to 7 is considered intermediate. 8 to 9 is considered high. [26]
Cell division becomes uncontrolled. Cell nuclei become less uniform. Pathologists describe cells as well differentiated (low-grade), moderately differentiated (intermediate-grade), and poorly differentiated (high-grade) as the cells progressively lose the features seen in normal breast cells. Poorly differentiated cancers have a worse prognosis ...
Danielle Fishel has breast cancer.. The Boy Meets World, star, 43, shared that she was recently diagnosed with an early form of breast cancer called ductal carcinoma in situ (DCIS), in the latest ...
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