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Contents. Colchicine. Colchicine is a medication used to prevent and treat gout, [ 3 ][ 4 ] to treat familial Mediterranean fever [ 5 ] and Behçet's disease, [ 6 ] and to reduce the risk of myocardial infarction. [ 7 ] The American College of Rheumatology recommends colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids in the ...
An ECG showing pericarditis. Note the ST elevation in multiple leads with slight reciprocal ST depression in aVR. Acute pericarditis is a type of pericarditis (inflammation of the sac surrounding the heart, the pericardium) usually lasting less than 4 to 6 weeks. [1] It is the most common condition affecting the pericardium.
Pericarditis is inflammation of the pericardium, the fibrous sac surrounding the heart. [ 8 ] Symptoms typically include sudden onset of sharp chest pain, which may also be felt in the shoulders, neck, or back. [ 1 ] The pain is typically less severe when sitting up and more severe when lying down or breathing deeply. [ 1 ]
Colchicine has been used effectively to prevent pericarditis, and inflammation that follows surgery of the pericardium. [5] Although no current drug on the market prevents post-pericardiotomy syndrome, colchicine seems to provide an effective and safe way to treat pericarditis by reducing inflammation. [ 6 ]
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Dressler syndrome. Dressler syndrome is a secondary form of pericarditis that occurs in the setting of injury to the heart or the pericardium (the outer lining of the heart). It consists of fever, pleuritic pain, pericarditis and/or pericardial effusion. Dressler syndrome is also known as postmyocardial infarction syndrome[1] and the term is ...
Colchicine (Colcrys) for pericarditis: colchicine is indicated for the treatment and prevention of gout, though it is also generally considered first-line treatment for acute pericarditis, as well as preventing recurrent episodes. Although the exact mechanism of colchicine is not fully understood, its anti-inflammatory effect for pericarditis ...
Purulent Pericarditis; Echocardiogram showing pericardial effusion with signs of cardiac tamponade: Specialty: Cardiology: Symptoms: substernal chest pain (exacerbated supine and with breathing deeply), dyspnea, fever, rigors/chills, and cardiorespiratory signs (i.e., tachycardia, friction rub, pulsus paradoxus, pericardial effusion, cardiac tamponade, pleural effusion)