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Pimecrolimus is an immunosuppressant drug of the calcineurin inhibitor class used in the treatment of atopic dermatitis (eczema). It is available as a topical cream. It was developed and formerly marketed by Novartis under the trade name Elidel .
An open-label pilot study found that topical pimecrolimus cream helped dark-skinned patients with postinflammatory hypopigmentation related to seborrheic dermatitis. [ 8 ] When functional melanocytes are present in the damaged area, sun or ultraviolet (UV) exposure may aid in repigmentation; however, excessive exposure may intensify the color ...
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After the withdrawal period is over, the atopic dermatitis can cease or is less severe than it was before. [8] Topical steroid addiction has also been reported in the male scrotum area. [ 9 ] Other symptoms include nerve pain, insomnia, excessive sweating, anxiety, severe depression, fatigue, eye problems, and frequent infections.
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Topical immunosuppressants like pimecrolimus and tacrolimus may be better in the short term and appear equal to steroids after a year of use. [66] Their use is reasonable in those who do not respond to or are not tolerant of steroids. [67] [68] Treatments are typically recommended for short or fixed periods of time rather than indefinitely.
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