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Acinar cell carcinoma of the pancreas, also acinar cell carcinoma, is a rare malignant exocrine tumour of the pancreas. It represents 5% of all exocrine tumours of the pancreas, making it the second most common type of pancreatic cancer. [1] It is abbreviated ACC. It typically has a guarded prognosis.
These tumors, which resemble serous acinar cells, vary in their behavior from locally aggressive to blatantly malignant. It can also appear in the breast. The pancreatic form of acinic cell carcinoma is a rare subtype of exocrine pancreatic cancer. Exocrine pancreatic cancers are the most common form of pancreatic cancer when compared to ...
Pancreatic acinar metaplasia (PAM) is a common incidental histopathologic finding present in approximately 20-25% of patients undergoing an esophagogastroduodenoscopy ...
What is pancreatic cancer? The pancreas is a 6-inch long gland that lies between the stomach and the spine, the National Cancer Institute noted.It helps the body break down food and regulate blood ...
A pancreatic tumor is an abnormal growth in the pancreas. [1] In adults, almost 90% are pancreatic cancer and a few are benign. [1] Pancreatic tumors are rare in children. [1] Classification is based on cellular differentiation (ductal, acinar, neuroendocrine, other) and gross appearance (intraductal, cystic, solid). [1]
Pancreatic cancer can be treated with surgery, radiotherapy, chemotherapy, palliative care, or a combination of these. [1] Treatment options are partly based on the cancer stage. [1] Surgery is the only treatment that can cure pancreatic adenocarcinoma, [12] and may also be done to improve quality of life without the potential for cure.
The pancreas contains tissue with an endocrine and exocrine role, and this division is also visible when the pancreas is viewed under a microscope. [10] The majority of pancreatic tissue has a digestive role. The cells with this role form clusters (Latin: acini, lit. 'kernels') around small ducts, and are arranged in lobes that have thin ...
They are typically solid, soft masses. Under the microscope, at least two cell types are seen: cells with “acinar” differentiation, and cells forming small “squamoid” nests. The cells with acinar differentiation have some features of the normal acinar cell of the pancreas (the most common cell in the normal pancreas). [5]
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