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Fungemia is the presence of fungi or yeast in the blood. The most common type, also known as candidemia , candedemia , or systemic candidiasis , is caused by Candida species. Candidemia is also among the most common bloodstream infections of any kind. [ 1 ]
Invasive candidiasis is an infection (candidiasis) that can be caused by various species of Candida yeast. Unlike Candida infections of the mouth and throat (oral candidiasis) or vagina (Candidal vulvovaginitis), invasive candidiasis is a serious, progressive, and potentially fatal infection that can affect the blood (), heart, brain, eyes, bones, and other parts of the body.
Blood is normally sterile. [1] The presence of bacteria in the blood is termed bacteremia, and the presence of fungi is called fungemia. [2] Minor damage to the skin [3] or mucous membranes, which can occur in situations like toothbrushing or defecation, [4] [5] can introduce bacteria into the bloodstream, but this bacteremia is normally transient and is rarely detected in cultures because the ...
Two blood cultures drawn from separate sites of the body are often sufficient to diagnose bacteremia. [34] Two out of two cultures growing the same type of bacteria usually represents a real bacteremia, particularly if the organism that grows is not a common contaminant. [34] One out of two positive cultures will usually prompt a repeat set of ...
Cryptococcus neoformans is an encapsulated basidiomycetous yeast [1] belonging to the class Tremellomycetes and an obligate aerobe [2] that can live in both plants and animals. Its teleomorph is a filamentous fungus, formerly referred to Filobasidiella neoformans. In its yeast state, it is often found in bird excrement.
The yeast Candida albicans can live in people without producing symptoms, and is able to cause both superficial mild candidiasis in healthy people, such as oral thrush or vaginal yeast infection, and severe systemic candidiasis in those who cannot fight infection themselves.
Histoplasmosis can be diagnosed by samples containing the fungus taken from sputum (via bronchoalveolar lavage), blood, or infected organs. It can also be diagnosed by detection of antigens in blood or urine samples by ELISA or polymerase chain reaction .
The teleomorph was first described in 1975 by K.J. Kwon-Chung, who obtained cultures of the type species, Filobasidiella neoformans, by crossing strains of the yeast Cryptococcus neoformans. She was able to observe basidia similar to those of the genus Filobasidium, hence the name Filobasidiella for the new genus. [3]