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Paclitaxel, sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer. [11] It is administered by intravenous injection. [11] There is also an albumin-bound formulation. [11]
Protein-bound paclitaxel, also known as nanoparticle albumin–bound paclitaxel or nab-paclitaxel, is an injectable formulation of paclitaxel used to treat breast cancer, lung cancer and pancreatic cancer, among others. Paclitaxel kills cancer cells by preventing the normal breakdown of microtubules during cell division. [2] [3] [4] In this ...
The following is a list of some of the commonly used adjuvant chemotherapy for breast cancer: CMF: cyclophosphamide, methotrexate, and 5-fluorouracil. [4] FAC (or CAF): 5-fluorouracil, doxorubicin, cyclophosphamide. [5] AC (or CA): Adriamycin (doxorubicin) and cyclophosphamide. [6] AC-Taxol: AC followed by paclitaxel (Taxol). [7]
Side-effects of treatment can include scarring, skin changes, heart damage from radiation and lymphoedema, a painful swelling of the arm, according to Dr Tim Rattay, a consultant breast surgeon ...
Docetaxel and paclitaxel have comparable efficacy metastatic breast cancer but paclitaxel has less severe side effects. [21] Additionally, it has been noted that docetaxel is prone to cellular drug resistance via a variety of different mechanisms.
Paclitaxel is also known as Taxol and Onxol to be an anti-cancer drug. The drug is the first line treatment for ovarian, breast, lung, and colon cancer and the second line treatment for AIDS-related Kaposi's sarcoma. (Kaposi sarcoma is a cancer of the skin and mucous membranes that is commonly found in patients with acquired immunodeficiency ...
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