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The plate is only found in children and adolescents; in adults, who have stopped growing, the plate is replaced by an epiphyseal line. This replacement is known as epiphyseal closure or growth plate fusion. Complete fusion can occur as early as 12 for girls (with the most common being 14–15 years for girls) and as early as 14 for boys (with ...
Epiphyseal growth plate: This transverse layer lies between the epiphysis and diaphysis. It’s composed of highly active chondrocytes and responsible for longitudinal bone growth. Consequently, the bone elongates at this growth plate until closure occurs at skeletal maturity.
An epiphyseal line is an epiphyseal plate that has become ossified. [1] The process of it forming from an epiphyseal plate is named epiphyseal closure. [2] In adult humans, it marks the point of fusion between the epiphysis and the metaphysis. [3] [4]
Many bones in the body contain an epiphysis, a region critical for growth and articulation. The humerus, for example, is situated between the shoulder and elbow and contributes significantly to upper limb movement. Below the elbow are the radius and ulna, two bones that run parallel to each other.
Brachyphalangy of the distal phalange of the thumb. This condition is caused by either fusion or early closure of the phalange's growth plate. One example is brachydactyly type D, which is caused by an early closure of the thumb's distal phalange, leading to a congenitally short thumb with a similarly short and wide thumb nail.
Early skeletal deformities can arise in infants such as soft, thinned skull bones – a condition known as craniotabes, [15] [16] which is the first sign of rickets; skull bossing may be present and a delayed closure of the fontanelles. Young children may have bowed legs and thickened ankles and wrists; [17] older children may have knock knees ...
Trigonocephaly is a result from the premature closure of the metopic suture. [10] [11] According to Virchow's law, this fusion will result in a narrow forehead, which is even further emphasized by ridging of the suture. [10] [11] Compensatory growth occurs at both the coronal sutures, thereby pushing the forehead forwards.
Acromegaly is a disorder that results in excess growth of certain parts of the human body. It is caused by excess growth hormone (GH) after the growth plates have closed. The initial symptom is typically enlargement of the hands and feet. [3] There may also be an enlargement of the forehead, jaw, and nose.