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Leukocyte esterase (LE) is an esterase (a type of enzyme) produced by leukocytes (white blood cells). A leukocyte esterase test (LE test) is a urine test for the presence of white blood cells and other abnormalities associated with infection. White blood cells in the urine can indicate a urinary tract infection (UTI). Positive test results may ...
The leukocyte esterase test indirectly detects the presence of leukocytes (white blood cells) in urine which can be associated with a urinary tract infection. In the elderly, the leukocyte esterase test is often positive even in the absence of an infection.
The urine test strip reaction is based on the action of leukocyte esterase in catalysing the hydrolysis of an ester of indolecarboxylic acid. The indoxyl that is liberated combines with a diazonium salt in order to produce a violet coloured azole dye. [21] 1) Reaction catalysed by leukocyte esterase
Because the test pad reaction is dependent on pH, false positive results can occur if the urine is highly alkaline. [ 60 ] [ 62 ] Conventional test strips are not sensitive enough to reliably detect microalbuminuria , a condition in which urine albumin levels are slightly elevated, [ 64 ] although dipsticks specialized for this measurement exist.
Another test, urine microscopy, looks for the presence of red blood cells, white blood cells, or bacteria. Urine culture is deemed positive if it shows a bacterial colony count of greater than or equal to 10 3 colony-forming units per mL of a typical urinary tract organism. Antibiotic sensitivity can also be tested with these cultures, making ...
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That said, Vanessa Rissetto, R.D., co-founder of the virtual nutrition care service Culina Health, believes the FDA's move is a positive step forward."Early-stage cancers are on the rise across ...