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  2. Proteus syndrome - Wikipedia

    en.wikipedia.org/wiki/Proteus_syndrome

    Proteus syndrome is a rare genetic disorder [1] that can cause tissue overgrowth involving all three embryonic lineages. Patients with Proteus syndrome tend to have an increased risk of embryonic tumor development. [2] The clinical symptoms and radiographic findings of Proteus syndrome are highly variable, as are its orthopedic manifestations ...

  3. Bannayan–Riley–Ruvalcaba syndrome - Wikipedia

    en.wikipedia.org/wiki/Bannayan–Riley...

    Bannayan–Riley–Ruvalcaba syndrome; Other names: BRRS: Autosomal dominant is the manner in which this condition is inherited: Specialty: Oncology, medical genetics Symptoms: Enlarged head [1] Causes: Mutations in the PTEN gene [2] Diagnostic method: Based on signs and symptoms [3] Treatment: Based on symptoms [3]

  4. Multisystem developmental disorder - Wikipedia

    en.wikipedia.org/wiki/Multisystem_developmental...

    Multisystem developmental disorder (MSDD) is a term used by Stanley Greenspan to describe children under age 3 who exhibit signs of impaired communication as in autism, but with strong emotional attachments atypical of autism. [citation needed] It is described in the DC:0-3R manual as an optional diagnosis for children under two years of age ...

  5. Overgrowth syndrome - Wikipedia

    en.wikipedia.org/wiki/Overgrowth_syndrome

    Children with some overgrowth syndromes such as Klippel–Trénaunay syndrome can be readily detectable at birth. [3] In contrast, other overgrowth syndromes such as Proteus syndrome usually present in the postnatal period, characteristically between the second and third year of life. [2]

  6. Mandy Sellars - Wikipedia

    en.wikipedia.org/wiki/Mandy_Sellars

    In 2006, some doctors diagnosed Sellars as having Proteus syndrome, a very rare condition thought to affect only 120 people worldwide, [1] but more recent diagnoses have focused on a PIK3CA gene mutation. Some reports still describe her condition as a rare form of Proteus syndrome, [2] but Sellars herself has disputed the diagnosis. [3]

  7. VACTERL association - Wikipedia

    en.wikipedia.org/wiki/VACTERL_association

    The VACTERL association (also VATER association, and less accurately VACTERL syndrome) refers to a recognized group of birth defects which tend to co-occur (see below).This pattern is a recognized association, as opposed to a syndrome, because there is no known pathogenetic cause to explain the grouped incidence.

  8. Phakomatosis - Wikipedia

    en.wikipedia.org/wiki/Phakomatosis

    Many require lifelong surveillance and various treatments depending on the particular syndrome and presentation. Phakomatoses , also known as neurocutaneous syndromes , are a group of multisystemic diseases that most prominently affect structures primarily derived from the ectoderm such as the central nervous system, skin and eyes.

  9. Proteus-like syndrome - Wikipedia

    en.wikipedia.org/wiki/Proteus-like_syndrome

    Proteus-like syndrome (PLS) is a condition similar to Proteus syndrome, but with an uncertain cause. [1] It's characterized by skeletal and hamartous overgrowth of multiple tissues, nevi in cerebriform connective tissue, blood vessel malformations and linear epidermal nevi. [2] [3]