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For a 20 g mouse, flow rates of about 200 ml/min through 500 ml containers would provide a good balance. At this flow rate, about 40 ml of O 2 is brought to the chamber and the entire volume of air in the chamber is exchanged within 5 minutes. For other smaller animals, chamber volumes can be much smaller and flow rates would be adjusted down ...
A respirometer is a device used to measure the rate of respiration [1] of a living organism by measuring its rate of exchange of oxygen and/or carbon dioxide. [2] They allow investigation into how factors such as age, or chemicals affect the rate of respiration. [3]
The tracer gas is analyzed simultaneously with CO to determine the distribution of the test gas mixture. This test will pick up diffusion impairments, for instance in pulmonary fibrosis. [ 22 ] This must be corrected for anemia (a low hemoglobin concentration will reduce DLCO) and pulmonary hemorrhage (excess RBC's in the interstitium or ...
Based on the results of Gonfiantini (1978), the IAEA defined the delta scale with SLAP at −55.5‰ for 18 O and −428‰ for 2 H. That is, SLAP was measured to contain approximately 5.55% less oxygen-18 and 42.8% less deuterium than does VSMOW, and these figures were used to anchor the scale at two points. [8] Experimental figures are given ...
Fraction of inspired oxygen (F I O 2), correctly denoted with a capital I, [1] is the molar or volumetric fraction of oxygen in the inhaled gas. Medical patients experiencing difficulty breathing are provided with oxygen-enriched air, which means a higher-than-atmospheric F I O 2. Natural air includes 21% oxygen, which is equivalent to F I O 2 ...
Indirect calorimetry is the study or clinical use of the relationship between respirometry and bioenergetics, where the measurement of the rates of oxygen consumption, sometimes carbon dioxide production, and less often urea production is transformed to rates of energy expenditure, expressed as the ratio between i) energy and ii) the time frame ...
The respiratory exchange ratio (RER) is the ratio between the metabolic production of carbon dioxide (CO 2) and the uptake of oxygen (O 2). [3] [4] The ratio is determined by comparing exhaled gases to room air. Measuring this ratio is equal to RQ only at rest or during mild to moderate aerobic exercise without the accumulation of lactate.
Gas is breathed at ambient pressure, and some of this gas dissolves into the blood and other fluids. Inert gas continues to be taken up until the gas dissolved in the tissues is in a state of equilibrium with the gas in the lungs (see saturation diving), or the ambient pressure is reduced until the inert gases dissolved in the tissues are at a higher concentration than the equilibrium state ...