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Anti-inflammatories like aspirin and ibuprofen, as well as blood thinners, affect the blood’s ability to clot, per the Mayo Clinic, which can lead to excess leakage when a capillary bursts upon ...
[1] [4] Complications can include swelling of the brain or lungs, seizures, low blood sugar, or cardiac arrest. [1] While usually due to aspirin, other possible causes include oil of wintergreen and bismuth subsalicylate. [2] Excess doses can be either on purpose or accidental. [1] Small amounts of oil of wintergreen can be toxic. [2]
Aspirin is non-selective and irreversibly inhibits both forms [4] (but is weakly more selective for COX-1 [5]). It does so by acetylating the hydroxyl of a serine residue at the 530 amino acid position. [6] Normally COX produces prostaglandins, most of which are pro-inflammatory, and thromboxanes, which promote clotting.
Aspirin can induce swelling of skin tissues in some people. In one study, angioedema appeared one to six hours after ingesting aspirin in some of the people. However, when the aspirin was taken alone, it did not cause angioedema in these people; the aspirin had been taken in combination with another NSAID-induced drug when angioedema appeared ...
Aspirin helps prevent blood clots from forming, which is the leading cause of heart attack and stroke, but the drug also carries a risk of bleeding. That risk can outweigh aspirin’s benefits in ...
Bengay and similar products, such as Flexall, Mentholatum, Capzasin and Icy Hot, variously contain menthol, methyl salicylate (oil of wintergreen), and capsaicin as active ingredients and have a potential to cause first-to-third-degree chemical burns. [4] [5] Some people have been hospitalized after receiving such burns. [4]
Unexplained bruising may be a warning sign of child abuse, domestic abuse, or serious medical problems such as leukemia or meningoccocal infection. Unexplained bruising can also indicate internal bleeding or certain types of cancer. Long-term glucocorticoid therapy can cause easy bruising.
Every year, hundreds of thousands of people visit an emergency department due to self-inflicted injuries. Experts explain the psychology behind and treatment options for self-harm.