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Adrenaline, also known as epinephrine, is a hormone and medication [10] [11] which is involved in regulating visceral functions (e.g., respiration). [10] [12] It appears as a white microcrystalline granule. [13] Adrenaline is normally produced by the adrenal glands and by a small number of neurons in the medulla oblongata. [14]
The reaction begins in the amygdala, which triggers a neural response in the hypothalamus. The initial reaction is followed by activation of the pituitary gland and secretion of the hormone ACTH. [19] The adrenal gland is activated almost simultaneously, via the sympathetic nervous system, and releases the hormone epinephrine.
Adrenaline is released by the adrenal glands to begin the response in the body. Adrenaline acts as a catalyst for the fight-or-flight response, [11] which is a response of the sympathetic nervous system to encourage the body to react to the apparent stressor. This response causes an increase in heart-rate, blood pressure, and accelerated breathing.
The increase in activity of synthesis of norepinephrine and epinephrine within the medulla is done from glucocorticoids through the increase in reaction rate of certain enzymes, such as: tyrosine hydroxylase, aromatic L-amino acid decarboxylase, dopamine-β-hydroxylase, and phenylethanolamine N-methyltransferase. [4]
This chain reaction occurs when faced with a threatening situation. [6] Nearly two decades later, more came to be known about the impacts of high epinephrine. Studies suggest glucose, together with epinephrine from the adrenal medulla have an effect on memory.
Early experiments showed that adrenaline increases twitch, but not tetanic force and rate of force development in muscles. [38]One proposed explanation is Tim Noakes' "central governor" theory, which states that higher instances in the central nervous system dynamically and subconsciously control the number of active motor units in the muscle.
Epinephrine, also known as adrenaline, is also used commonly to respond to both internal and external changes. One common cause of the release of this hormone is the Fight-or-flight response. When the body encounters an external stimulus that is potentially dangerous, epinephrine is released from the adrenal glands. Epinephrine causes ...
There are several known causes of adrenergic storms; in the United States, cocaine overdose is the leading cause. [16] Any stimulant drug has the capacity to cause this syndrome if taken in sufficient doses, but even non-psychotropic drugs can very rarely provoke a reaction.