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Cochlear hydrops (or cochlear Meniere's or cochlear endolymphatic hydrops) is a condition of the inner ear involving a pathological increase of fluid affecting the cochlea. This results in swelling that can lead to hearing loss or changes in hearing perception.
Ménière's disease (MD) is a disease of the inner ear that is characterized by potentially severe and incapacitating episodes of vertigo, tinnitus, hearing loss, and a feeling of fullness in the ear. [3] [4] Typically, only one ear is affected initially, but over time, both ears may become involved. [3]
Autoimmune inner ear disease (AIED) was first defined by Dr. Brian McCabe in a landmark paper describing an autoimmune loss of hearing. [2] The disease results in progressive sensorineural hearing loss (SNHL) that acts bilaterally and asymmetrically, and sometimes affects an individual's vestibular system .
Ménière's disease – causes sensorineural hearing loss in the low frequency range (125 Hz to 1000 Hz). Ménière's disease is characterized by sudden attacks of vertigo, lasting minutes to hours preceded by tinnitus, aural fullness, and fluctuating hearing loss. It is relatively rare and commonly over diagnosed.
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Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.
Endolymphatic hydrops, edema in the inner ear, present in Ménière's disease; Cochlear hydrops, a variant of Meniere's disease/Endolymphatic Hydrops without vertigo. Hydrops fetalis, edema in a fetus; Corneal hydrops, humoral edema of the eye
Hara said the markers of Alzheimer’s disease can begin quite early in life without the presence of typical symptoms. She pointed to a number of interesting studies of the phenomenon.
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