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In population genetics, the Hardy–Weinberg principle, also known as the Hardy–Weinberg equilibrium, model, theorem, or law, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences.
Genetic equilibrium is the condition of an allele or genotype in a gene pool (such as a population) where the frequency does not change from generation to generation. [1] Genetic equilibrium describes a theoretical state that is the basis for determining whether and in what ways populations may deviate from it.
The IBD model is useful for determining the distribution of gene frequencies over a geographic region. [2] Both dispersal variance and migration probabilities are variables in this model and both contribute to local genetic differentiation. [3] Isolation by distance is usually the simplest model for the cause of genetic isolation between ...
Cell culture is a fundamental component of tissue culture and tissue engineering, as it establishes the basics of growing and maintaining cells in vitro. The major application of human cell culture is in stem cell industry, where mesenchymal stem cells can be cultured and cryopreserved for future use. Tissue engineering potentially offers ...
A model of a biological system is converted into a system of equations, although the word 'model' is often used synonymously with the system of corresponding equations. The solution of the equations, by either analytical or numerical means, describes how the biological system behaves either over time or at equilibrium .
Population genetics must either model this complexity in detail, or capture it by some simpler average rule. Empirically, beneficial mutations tend to have a smaller fitness benefit when added to a genetic background that already has high fitness: this is known as diminishing returns epistasis. [21]
Statistical tools such as the Mantel test or partial Mantel test are commonly used to correlate genetic patterns with landscape features. Linear regression models and ordination techniques are also common. [2] Geographic information systems (GIS) can be used to visualize genetic patterns across space by plotting genetic data on a map of the ...
Population structure (also called genetic structure and population stratification) is the presence of a systematic difference in allele frequencies between subpopulations. In a randomly mating (or panmictic ) population, allele frequencies are expected to be roughly similar between groups.
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