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Radiation-induced lung injury (RILI) is a general term for damage to the lungs as a result of exposure to ionizing radiation. [1] In general terms, such damage is divided into early inflammatory damage ( radiation pneumonitis ) and later complications of chronic scarring ( radiation fibrosis ).
Oklahoma CyberKnife is a cancer treatment center based in Oklahoma. The center treats malignant and benign tumors in the lungs, spine, brain, liver, pancreas, eye, prostate and kidney using CyberKnife technology. Oklahoma CyberKnife has treated patients from around Oklahoma as well as patients from bordering states.
Pulmonary fibrosis is not currently curable; but some steps can be taken to minimize its effects, such as changing the treatment regimen. Other measures that should be taken into account are quitting smoking (if applicable), oxygen therapy, pulmonary rehabilitation, vaccination against influenza and pneumococcus to prevent lung infections, or in extreme cases, a lung transplant.
Lung symptoms in a patient who is taking a medicinal drug that can cause pulmonary toxicity should not automatically lead to a diagnosis of "pulmonary toxicity due to the medicinal drug", because some patients can have another (i.e., simultaneous) lung disease, e.g. an infection of the lungs not related to the medicinal drugs the patient is ...
It is caused by cigarette smoking. [1] [2] The term SRIF was coined by Dr. Anna-Luise Katzenstein (a pathologist) and colleagues in 2010 in a study of lung specimens surgically removed for lung cancer. [3] Since then, other investigators have confirmed the same abnormality in the lungs of a subset of smokers. [4] [5]
The main treatment for DIP is quitting smoking. Sometimes smoking cessation is successful in managing DIP however in some cases this is not enough. Avoidance of other potential environmental factors is also advised. In those who are moderately to severely symptomatic and who have not responded to quitting smoking, corticosteroids are used.
The inaugural CyberKnife system was installed at Stanford University in 1991, receiving clearance for clinical investigation by the U.S. Food and Drug Administration (FDA) in 1994. Following extensive clinical research , the FDA granted approval for the treatment of intracranial tumors in 1999 and for tumors throughout the body in 2001.
A recent article on mortality in a cohort of 8,645 smokers who were followed up after 43 years determined that "current smoking and lifetime persistent smoking were associated with an increased risk of all-cause, CVD [cardiovascular disease], COPD [chronic obstructive pulmonary disease], and any cancer, and lung cancer mortality."