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The inflammation caused by rheumatic fever, usually during childhood, is referred to as rheumatic valvulitis. About half of patients with rheumatic fever develop inflammation involving valvular endothelium. [19] The majority of morbidity and mortality associated with rheumatic fever is caused by its destructive effects on cardiac valve tissue. [18]
Myocarditis refers to an underlying process that causes inflammation and injury of the heart. It does not refer to inflammation of the heart as a consequence of some other insult. Many secondary causes, such as a heart attack, can lead to inflammation of the myocardium and therefore the diagnosis of myocarditis cannot be made by evidence of ...
Inflammatory damage leads to the following: [1] [2] Pericarditis: Here the pericardium gets inflamed. Acutely, it can cause pericardial effusion leading to cardiac tamponade and death. After healing, there may be fibrosis and adhesion of the pericardium with the heart leading to constriction of the heart and reduced cardiac function.
ROS, alone, cause more than 20 types of DNA damage. [50] Oxidative DNA damages cause both mutations [51] and epigenetic alterations. [52] [46] [53] RNS also cause mutagenic DNA damages. [54] A normal cell may undergo carcinogenesis to become a cancer cell if it is frequently subjected to DNA damage during long periods of chronic inflammation ...
[3] [4] [10] Note: Fever and an increased white blood cell count are features of the acute-phase reaction, while an increased heart rate is often the initial sign of hemodynamic compromise. An increased rate of breathing may be related to the increased metabolic stress due to infection and inflammation, but may also be an ominous sign of ...
“A COVID-19 infection can directly damage the heart,” Dr. Harlan Krumholz said. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ...
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