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Styrene oxide is a main metabolite of styrene in humans or animals, resulting from oxidation by cytochrome P450. It is considered possibly carcinogenic from gavaging significant amounts into mice and rats. [4] Styrene oxide is subsequently hydrolyzed in vivo to styrene glycol by epoxide hydrolase. [5]
Styrene is regarded as a "known carcinogen", especially in case of eye contact, but also in case of skin contact, of ingestion and of inhalation, according to several sources. [20] [33] [34] [35] Styrene is largely metabolized into styrene oxide in humans, resulting from oxidation by cytochrome P450.
Residents near Cleves are being urged to leave their homes Tuesday afternoon because a rail car is leaking styrene. What to know about the chemical.
Chronic solvent-induced encephalopathy (CSE) is a condition induced by long-term exposure to organic solvents, often—but not always—in the workplace, that lead to a wide variety of persisting sensorimotor polyneuropathies and neurobehavioral deficits even after solvent exposure has been removed.
Here's what the Drug & Poison Information Center at Cincinnati Children’s Hospital advises regarding returning home following the styrene leak.
The Visakhapatnam gas leak, also referred to as the Vizag gas leak, was an industrial accident that occurred at the LG Polymers chemical plant in the R. R. Venkatapuram village of the Gopalapatnam neighbourhood, located at the outskirts of Visakhapatnam, Andhra Pradesh, India, during the early morning of 7 May 2020.
Siefke said that air monitoring for styrene had begun as officials attempted to collect data to determine whether the evacuation and shelter-in-place orders were set appropriately.
Pulmonary toxicity is the medical name for side effects on the lungs. Although most cases of pulmonary toxicity in medicine are due to side effects of medicinal drugs, many cases can be due to side effects of radiation (radiotherapy). Other (non-medical) causes of pulmonary toxicity can be chemical compounds and airborne particulate matter.