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The DRKS is an open access, free of charge online register for clinical trials and is available both in English and German. DRKS is part of the WHO's ICTRP. The DRKS works with two partner registries in Germany, DeReG (German Registry for Somatic Gene-Transfer Trials) and Clinical Trial Registry of the University Medical Center Freiburg. [4]
As a result of pressure from HIV-infected men in the gay community, [citation needed] who demanded better access to clinical trials, the U.S. Congress passed the Health Omnibus Programs Extension Act of 1988 (Public Law 100-607) [2] which mandated the development of a database of AIDS Clinical Trials Information Services (ACTIS). [3]
Independent clinical studies are of key importance for improving the effectiveness, safety and cost/benefit balance, such as the long-term risks and rare adverse reactions to treatments, comparing the available treatment options, evaluating the hoped-for improvements in quality of life or in follow-up of procedures and rehabilitation strategies.
Systematic reviews and meta-analyses of randomized controlled trials can provide strong evidence of the clinical efficacy of particular treatments in given scenarios, which may, in turn, be incorporated into medical guidelines or institutional position papers (ideal sources for clinical recommendations). It is normally best to use reviews and ...
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A clinical trial participant receives an injection. Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further ...
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