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  2. Which Allergy Medicine Is Actually Most Effective? - AOL

    www.aol.com/allergy-medicine-actually-most...

    “This is a second-generation antihistamine, which is less sedating than the first-generation antihistamines like Benadryl,” says Shaan Waqar, MD, an allergist and immunologist with ENT and ...

  3. Hydroxyzine - Wikipedia

    en.wikipedia.org/wiki/Hydroxyzine

    It is a first-generation antihistamine in the piperazine family of chemicals. [8] [4] Common side effects include sleepiness, headache, and dry mouth. [8] [9] Serious side effects may include QT prolongation. [9] It is unclear if use during pregnancy or breastfeeding is safe. [8]

  4. Anti-allergic agent - Wikipedia

    en.wikipedia.org/wiki/Anti-allergic_agent

    First-generation antihistamines usually last around 4–6 hours whilst second-generation antihistamines work for 12–24 hours. [7] Third generation antihistamines are metabolites of the second-generation antihistamines but without cardiac toxicity. [8] Indications and route of administration

  5. Doxylamine - Wikipedia

    en.wikipedia.org/wiki/Doxylamine

    Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.

  6. Chlorphenamine - Wikipedia

    en.wikipedia.org/wiki/Chlorphenamine

    It is a first-generation antihistamine and works by blocking the histamine H 1 receptor. [2] Common side effects include sleepiness, restlessness, and weakness. Other side effects may include dry mouth and wheeziness. [2] Chlorpheniramine was patented in 1948 and came into medical use in 1949. [3] It is available as a generic medication and ...

  7. Clemastine - Wikipedia

    en.wikipedia.org/wiki/Clemastine

    Clemastine, also known as meclastin, is a first-generation H1 histamine antagonist (antihistamine) with anticholinergic properties (drying) and sedative side effects. [1] Like all first-generation antihistamines, it is sedating. [2] [3] Patented in 1960, it came into medical use in 1967. [4]

  8. Sominex - Wikipedia

    en.wikipedia.org/wiki/Sominex

    In July 1975, the J. B. Williams Co. began marketing Sominex 2. [37] On November 24, 1975, Attorney General Evelle J. Younger filed suit on behalf of the State of California against Williams Co., stating that the product did not warn against use by pregnant or nursing women or persons with asthma or COPD, nor did it notify consumers that it should not be used in conjunction with alcohol. [38]

  9. Bamipine - Wikipedia

    en.wikipedia.org/wiki/Bamipine

    Side effects are typical of an old (first-generation) antihistamine: tiredness in adults, agitation in children, mydriasis (dilation of the pupils). These effects are rare when bamipine is applied topically as an ointment. Allergic and hypersensitivity reactions are also rare. Acute eczema can be worsened by bamipine ointment.