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Anthrax is a disease caused by Bacillus anthracis, a spore-forming, Gram positive, rod-shaped bacterium (Fig. 1).The lethality of the disease is caused by the bacterium's two principal virulence factors: (i) the polyglutamic acid capsule, which is anti-phagocytic, and (ii) the tripartite protein toxin, called anthrax toxin.
Precautions are taken to avoid contact with the skin and any fluids exuded through natural body openings of a deceased body that is suspected of harboring anthrax. [48] The body should be put in strict quarantine. A blood sample is collected and sealed in a container and analyzed in an approved laboratory to ascertain if anthrax is the cause of ...
The symptoms in anthrax depend on the type of infection and can take anywhere from 1 day to more than 2 months to appear. All types of anthrax have the potential, if untreated, to spread throughout the body and cause severe illness and even death. [24] Four forms of human anthrax disease are recognized based on their portal of entry.
It was killing people, one at a time, day by day. Between October 5, and November 22, 2001, five people who were exposed died from anthrax poisoning. Seeking experts. Anthrax. Saddam Hussein? Bin ...
Anthrax toxin receptor 1 (ANTXR1 or also known asTEM8) is a protein that in humans is encoded by the ANTXR1 gene. [ 5 ] [ 6 ] [ 7 ] Its molecular weight is predicted as about 63kDa. The protein encoded by this gene is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer.
Glycine is an important amino acid that is essential for adequate nervous system function aiding in cell communication throughout the body. When tetanus toxin enters the body it is taken up by cholinergic nerve endings traveling axonally into the brain and spinal cord, disrupting motor function in individuals. Although tetanus is a damaging ...
Symptoms depend on how anthrax enters the body. When it is spread through a cut or scratch on the skin, people may experience small blisters or bumps that itch, an ulcer with a black center after ...
Anthrax toxins: The protective antigen (PA) is the "B" component shared by the two "A" toxins in B. anthracis: the edema factor (EF) and the lethal factor (LF). [ 8 ] [ 9 ] LF is a Zn metalloprotease that cleaves MAPKK ; EF is a adenylate cyclase that targets protein kinases.