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Collagen IV (ColIV or Col4) is a type of collagen found primarily in the basal lamina. The collagen IV C4 domain at the C-terminus is not removed in post-translational processing, and the fibers link head-to-head, rather than in parallel. Also, collagen IV lacks the regular glycine in every third residue necessary for the tight, collagen helix ...
1285 12828 Ensembl ENSG00000169031 ENSMUSG00000079465 UniProt Q01955 Q9QZS0 RefSeq (mRNA) NM_000091 NM_031362 NM_031363 NM_031364 NM_031365 NM_031366 NM_007734 RefSeq (protein) NP_000082 NP_031760 Location (UCSC) Chr 2: 227.16 – 227.31 Mb Chr 1: 82.56 – 82.7 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Collagen alpha-3(IV) chain is a protein that in humans is encoded by the ...
The Pauling's book How to Live Longer and Feel Better, [92] first published in 1986, [93] was a bestseller and advocated taking more than 10 grams per day orally, thus approaching the amounts released by the liver directly into the circulation in other mammals: an adult goat, a typical example of a vitamin C–producing animal, will manufacture ...
For the European Union, the EFSA set higher recommendations for adults, and also for children: 20 mg/day for ages 1–3, 30 mg/day for ages 4–6, 45 mg/day for ages 7–10, 70 mg/day for ages 11–14, 100 mg/day for males ages 15–17, 90 mg/day for females ages 15–17. For pregnancy 100 mg/day; for lactation 155 mg/day. [20]
The ratio and the proportion of collagen play an important role in the tensile and compressive strength, as well as the elasticity of the tissue. The content of collagen in cartilage is different between joints and soft tissue structures. [3] For example, cartilage in the knee has a different structure to the ankle. Cartilage, skin, and spinal ...
Collagen is also abundant in corneas, blood vessels, the gut, intervertebral discs, and the dentin in teeth. [3] In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes 1% to 2% of muscle tissue and 6% by weight of skeletal muscle. [4] The fibroblast is the most common cell creating collagen in animals.