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Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).
Allergic rhinitis (AR) is a common condition where exposure to allergens results in the release of inflammatory mediators, such as histamine, that causes sneezing, rhinorrhea, itchy eyes, and nasal congestion. [7] The increased rhinorrhea and mucus production can result in PND.
Sinusitis is a condition that affects both children and adults. It is caused by a combination of environmental and a person's individual health factors. [8] It can occur in individuals with allergies, exposure to environmental irritants, structural abnormalities of the nasal cavity and sinuses and poor immune function. [9]
Anti-asthmatic agents, also known as anti-asthma drugs, refer to drugs that can aid in airway smooth muscle dilation to allow normal breathing during an asthma attack or reduce inflammation on the airway to decrease airway resistance for asthmatic patients, or both. The goal of asthmatic agents is to reduce asthma exacerbation frequencies and ...
However, asthma is rarely the only symptom, and not all people with food or other allergies have asthma [17] Sulfite sensitivity Asthma can occur in reaction to ingestion or inhalation of sulfites, which are added to foods and wine as preservatives. [18] Salicylate sensitivity Salicylates can trigger asthma in sensitive individuals. Salicylates ...
The most common signs and symptoms of an asthma attack include coughing, shortness of breath, feeling winded, a tightening in the chest, and a wheezing that makes a high-pitched whistling sound ...
[1] [5] It can manifest in adults with exposure to high levels of chlorine, ammonia, acetic acid, or sulphur dioxide, creating symptoms like asthma. [6] These symptoms can vary from mild to fatal and can even create long-term airway damage, depending on the amount of exposure and the concentration of chlorine.
Asthma triggers are factors or stimuli that provoke the exacerbation of asthma symptoms or increase the degree of airflow disruption, which can lead to an asthma attack. [1] An asthma attack is characterized by an obstruction of the airway , hypersecretion of mucus and bronchoconstriction due to the contraction of smooth muscles around the ...