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A dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion [1]) is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve. The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia. [2] The axons of dorsal root ganglion neurons are known as afferents.
Cross section of the spinal cord showing the subarachnoid cavity, and spinal nerve roots including the dorsal root ganglion. A neurolytic block is the deliberate injury of a nerve by the application of chemicals (in which case the procedure is called "neurolysis") or physical agents such as freezing or heating ("neurotomy"). [9]
A ganglionectomy, also called a gangliectomy, is the surgical removal of a ganglion. [1] The removal of a ganglion cyst usually requires a ganglionectomy. Such cysts usually form on the hand, foot or wrist and may cause pain or impair body function.
The dorsal root ganglion contains cell bodies for sensory nerves including large, myelinated Aβ fibers which carry proprioception and tactile touch sensation to the brain via the dorsal column–medial lemniscus pathway and small, unmyelinated C fibers which carry thermal and pain sensation to the brain via the spinothalamic tract. [2]
Selective dorsal rhizotomy (SDR), less often referred to as selective posterior rhizotomy (SPR), is the most widely used form of rhizotomy, and is today a primary treatment for spastic diplegia, best done in the youngest years before bone and joint deformities from the pull of spasticity take place.
Nerve block or regional nerve blockade is any deliberate interruption of signals traveling along a nerve, often for the purpose of pain relief. Local anesthetic nerve block (sometimes referred to as simply "nerve block") is a short-term block, usually lasting hours or days, involving the injection of an anesthetic, a corticosteroid, and other agents onto or near a nerve.
Tarlov cysts are most commonly located in the S1 to S4/S5 region of the spinal canal, but can be found along any region of the spine.They usually form on the extradural components of sacrococcygeal nerve roots at the junction of dorsal root ganglion and posterior nerve roots and arise between the endoneurium and perineurium. [10]
Dorsal root ganglion stimulation is a type of neurostimulation that is effective in the management of focal neuropathic pain. The FDA approved its use in February 2016. The ACCURATE Study demonstrated superiority of dorsal root ganglion stimulation over spinal (dorsal column) stimulation in the management of CRPS and causalgia. [62]