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The basal ganglia is a collective group of structures in the brain. These include the striatum, (composed of the putamen and caudate nucleus), globus pallidus, substantia nigra, and the subthalamic nucleus. Along with other structures, the basal ganglia are part of a neural circuit that is integral to voluntary motor function. [1]
Primary familial brain calcification [1] (PFBC), also known as familial idiopathic basal ganglia calcification (FIBGC) and Fahr's disease, [1] is a rare, [2] genetically dominant or recessive, inherited neurological disorder characterized by abnormal deposits of calcium in areas of the brain that control movement.
Neurodegeneration with brain iron accumulation is a heterogenous group of inherited neurodegenerative diseases, still under research, in which iron accumulates in the basal ganglia, either resulting in progressive dystonia, parkinsonism, spasticity, optic atrophy, retinal degeneration, neuropsychiatric, or diverse neurologic abnormalities. [1]
BTRBGD, [1] Biotin-responsive basal ganglia disease (BBGD), [2] Thiamine metabolism dysfunction syndrome 2 (biotin or thiamine-responsive type) (THMD2), [3] Thiamine-responsive encephalopathy, Thiamine transporter-2 deficiency [4] Specialty: Neurometabolic disorders, neurology, internal medicine: Symptoms
Basal ganglia disease is a group of movement disorders that result from either excessive output from the basal ganglia to the thalamus – hypokinetic disorders, or from insufficient output – hyperkinetic disorders. Hypokinetic disorders arise from an excessive output from the basal ganglia, which inhibits the output from the thalamus to the ...
As the GPi is one of the direct output centers of the basal ganglia, this causes disinhibition of the thalamus, increasing overall ease of initiating and maintaining movement. As this pathway only contains one synapse (from the striatum to the internal globus pallidus), it is known as the direct pathway. [4]
The coronavirus can damage the heart, according to a major new study which found abnormalities in the heart function of more than half of patients. The coronavirus can damage the heart, according ...
The name Bagadilico is an acronym formed using the two initial letters from the words Basal Ganglia Disorders Linnaeus Consortium. The group's ultimate goal is to find new therapies for Parkinson's disease and Huntington's disease. These disorders have in common that they are caused by disturbances in the part of the brain called the basal ...