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The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. [1]
Dry earwax is gray or tan and brittle, and is about 20% lipid. [5] It has a smaller concentration of lipid and pigment granules than wet earwax. [5] Wet earwax is light brown or dark brown and has a viscous and sticky consistency, and is about 50% lipid. [5] Wet-type earwax is associated with armpit odor, which is increased by sweat production ...
Those of animal origin typically consist of wax esters derived from a variety of fatty acids and carboxylic alcohols. In waxes of plant origin, characteristic mixtures of unesterified hydrocarbons may predominate over esters. [2] The composition depends not only on species, but also on geographic location of the organism.
Glucosylceramide is a major constituent of skin lipids, where it is essential for lamellar body formation in the stratum corneum and to maintain the water permeability barrier of the skin. Glucosylceramide is the only glycosphingolipid common to plants, fungi and animals. It is usually considered to be the principal glycosphingolipid in plants.
Long-chain fatty acids cannot cross the blood–brain barrier, but the liver can break these down to produce ketone bodies. However, short-chain fatty acids (e.g., butyric acid, propionic acid, and acetic acid) and the medium-chain fatty acids, octanoic acid and heptanoic acid, can cross the blood–brain barrier and be metabolised by brain cells.
Brain at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (view tree for regions of the brain) BrainMaps.org; BrainInfo (University of Washington) "Brain Anatomy and How the Brain Works". Johns Hopkins Medicine. 14 July 2021. "Brain Map". Queensland Health. 12 July 2022.
Wax esters per se are a normal part of the diet of humans as a lipid component of certain foods, including unrefined whole grain cereals, seeds, and nuts. [2] Wax esters are also consumed in considerable amounts by certain populations that regularly eat fish roe [6] or certain fish species. That said, wax esters are not typically consumed in ...
This lipid is found in a wide range of places. For example, in the human diet, about 130 mg are derived from phosphatidylserine. This has been said to have a positive impact on the brain, as it helps with reduced stress and improved memory. [10] Sphingomyelin. Sphingomyelin is a type of sphingolipid, which contains a backbone of sphingoid bases.