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It is a first-generation antihistamine and works by blocking the histamine H 1 receptor. [2] Common side effects include sleepiness, restlessness, and weakness. Other side effects may include dry mouth and wheeziness. [2] Chlorpheniramine was patented in 1948 and came into medical use in 1949. [3] It is available as a generic medication and ...
Coricidin, Coricidin 'D' (decongestant), or Coricidin HBP (for high blood pressure), is the name of an over-the-counter cough and cold drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (an antihistamine). [1] Introduced by Schering-Plough in 1949 as one of the first antihistamines, it is now owned by Bayer.
Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine.
Both products contained chlorpheniramine maleate (an antihistamine) and phenylpropanolamine hydrochloride (a decongestant) but differed in their doses. Both products contained 75 mg of phenylpropanolamine hydrochloride, but Cold Capsule IV contained 12 mg chlorpheniramine maleate while Cold Capsule V had 8 mg [ 1 ] .
Coricidin, Coricidin D, or Coricidin HBP, is the brand name of a combination of dextromethorphan and chlorpheniramine maleate (an antihistamine). [citation needed] Varieties may also contain acetaminophen and guaifenesin. [citation needed] Codral is a brand name manufactured by Johnson & Johnson and sold primarily in Australia and New Zealand ...
It also contains 237 million bioactivity test results from 1.25 million biological assays, covering >10,000 target protein sequences. [ 4 ] As of 2020, with data integration from over 100 new sources, PubChem contains more than 293 million depositor-provided substance descriptions, 111 million unique chemical structures, and 271 million ...
Chloropyramine is known as a competitive reversible H 1 receptor antagonist (also known as an H 1 inverse agonist), meaning that it exerts its pharmacological action by competing with histamine for the H 1 subtype histamine receptor. By blocking the effects of histamine, the drug inhibits the vasodilation, increased vascular permeability, and ...
It is often sold as a maleate salt, pyrilamine maleate. The medication has negligible anticholinergic activity, with 130,000-fold selectivity for the histamine H 1 receptor over the muscarinic acetylcholine receptors (for comparison, diphenhydramine had 20-fold selectivity for the H 1 receptor). [3] It was patented in 1943 and came into medical ...