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PSNs are diagnosed by examining the tissue under a microscope, usually obtained with a dilation and curettage.. Typically, they consist of pink (hyaline) material using the standard stain and contain few cells.
VUE is a T-cell mediated, CD8+ dominating inflammatory reaction. VUE develops in the foetal fibrovasculature stroma of the placenta villi usually towards the end of pregnancy (term placentas). [1] The lymphocytes in VUE are of maternal origin. VUE is a host-derived inflammatory response happening within a donor allograft tissue. The non-T-cell ...
The tumor may secrete human placental lactogen, [2] and result in a false-positive pregnancy test. [3] A placental site trophoblastic tumor is a monophasic neoplasm of the implantation site intermediate trophoblast, and usually a benign lesion, which comprises less than 2% of all gestational trophoblastic proliferations. Preceding conditions ...
VUE is a common lesion characterised by inflammation in the placental chorionic villi. VUE is also characterised by the transfer of maternal lymphocytes across the placenta. [4] VUE is diagnosed in 7–10% placentas in pregnancies. Roughly 80% of the VUE cases are in term placentas (greater than 37 weeks of pregnancy).
It is diagnosed by a microscopic examination of the placenta. Commonly used criteria from Altshuler [2] [3] are: "a minimum of 10 villi, each with 10 or more vascular channels, in 10 or more areas of 3 or more random, non-infarcted placental areas when using a ×10 ocular." The Altshuler criteria are not theoretically rigorous, as they do not ...
Implantation site intermediate trophoblast. Low molecular weight cytokeratin stain. Intermediate trophoblast is a distinct subtype of trophoblastic tissue that arises from the cytotrophoblast. [1] It is sub-categorized by location: [1] Villous intermediate trophoblast: at anchoring villi of trophoblastic column; Implantation site intermediate ...
Ischemic placental disease leads to the attachment of the placenta to the uterine wall to become under-perfused, causing uteroplacental ischemia. Where the term overarches the pathology associated with preeclampsia , placental abruptions and intrauterine growth restriction (IUGR). [ 3 ]
After ovulation, in placental mammals, the endometrial lining becomes hypertrophic and vascular under the influence of the sex hormones, estrogen and progesterone.. In animals exhibiting hemochorial placentation, the endometrium undergoes decidualization following implantation.