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Sebum: Sebum is an oily substance produced by sebaceous glands in the skin. While sebum plays a crucial role in keeping the skin moisturized and protected, it can also contribute to the ...
The application of 2% topical nicotinamide for 2 and 4 weeks has been found to be effective in lowering the sebum excretion rate. [20] Nicotinamide has been shown to prevent Cutibacterium acnes-induced activation of toll-like receptor 2, which ultimately results in the down-regulation of pro-inflammatory interleukin-8 production. [21]
Retinoids are medications that reduce inflammation, normalize the follicle cell life cycle, and reduce sebum production. [47] [97] They are structurally related to vitamin A. [97] Studies show dermatologists and primary care doctors underprescribe them for acne. [15] The retinoids appear to influence the cell life cycle in the follicle lining.
Nicomide is an acne medication available in topical cream, topical gel and vitamin supplement form (U.S. Patent No. 6,979,468). Tablets are available only by prescription and contain the active ingredients nicotinamide, zinc, copper, and folic acid.
“Similar to other acne, chin acne may be caused by a combination of factors including increased sebum production, clogged pores, inflammation, and bacteria,” says Marisa Garshick, M.D., F.A.A ...
The secret is a combination of biotin, saw palmetto and pumpkin seed oil that works in tandem to cleanse the scalp, gently exfoliate away sebum build-up, and promote blood flow and oxygen to the ...