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Periarteriolar lymphoid sheaths (or periarterial lymphatic sheaths, or PALS) are a portion of the white pulp of the spleen.They are populated largely by T cells and surround central arteries within the spleen; the PALS T-cells are presented with blood borne antigens via myeloid dendritic cells.
The cords of Billroth (also known as splenic cords or red pulp cords) are found in the red pulp of the spleen between the sinusoids, consisting of fibrils and connective tissue cells with a large population of monocytes and macrophages.
These macrophages are not unique to the spleen but instead make up an integral part of the lymphoid parts of all secondary lymphoid organs. In the B cell follicles, the macrophages are important in clearing the apoptotic B cells that occur during the germinal centre reaction in the process of somatic hypermutation and isotype switching.
Category: Histopathology of chronic venous congestion of liver Chronic venous congestion of spleen: Micrograph showing chronic venous congestion of spleen. Sinusoids are dialated. Organized foci of old hemorrhage seen as areas of fibrosis containing brown pigment (hemosiderin). Category: Histopathology of chronic venous congestion of spleen
Micrograph of the spleen showing darkly stained, spheroid Gamna-Gandy bodies (arrows) outside the vessel wall at the center. Also shown is diffusely scattered, brown, granular hemosiderin pigment (arrowheads), indicating previous hemorrhage (hematoxylin & eosin staining, 40x magnification).
The trabecular arteries are the name of the branches of the splenic artery after it passes into the trabeculae of the spleen, where it branches.When these arteries then reach the white pulp, and become covered with periarteriolar lymphoid sheaths, the name changes again to central arteries (or central arterioles).
White pulp, splenic lymphoid nodules, or white nodules — follicles in the white pulp of the spleen, containing many lymphocytes; These structures are named after Marcello Malpighi (1628–1694), an Italian physician and biologist regarded as the father of microscopical anatomy and histology