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  2. Etranacogene dezaparvovec - Wikipedia

    en.wikipedia.org/wiki/Etranacogene_dezaparvovec

    The safety and effectiveness of etranacogene dezaparvovec were evaluated by the US Food and Drug Administration (FDA) in two studies of 57 adult men 18 to 75 years of age with severe or moderately severe hemophilia B. [7] Effectiveness was established based on decreases in the men's annualized bleeding rate (ABR). [7]

  3. Gene therapy cures patients with hemophilia B - AOL

    www.aol.com/gene-therapy-cures-patients...

    Story at a glance Hemophilia B occurs when patients lack sufficient levels of the blood protein factor IX. Some current treatments for the condition involve repeated infusions of the protein. But ...

  4. Fidanacogene elaparvovec - Wikipedia

    en.wikipedia.org/wiki/Fidanacogene_elaparvovec

    In the US, fidanacogene elaparvovec is indicated for the treatment of adults with moderate to severe hemophilia B (congenital factor IX deficiency) who currently use factor IX prophylaxis therapy; or have current or historical life-threatening hemorrhage; or have repeated, serious spontaneous bleeding episodes; and do not have neutralizing antibodies to adeno-associated virus serotype Rh74var ...

  5. FDA approves CSL gene therapy for hemophilia - AOL

    www.aol.com/news/fda-approves-csls-gene-therapy...

    The companies expect the gene therapy to serve as a one-time shot to cut the rate of annual bleeding for hemophilia B patients, who represent about 15% of all patients with hemophilia. FDA ...

  6. FDA Approves Pfizer's Second Hemophilia Drug With Six Months

    www.aol.com/fda-approves-pfizers-second...

    Hympavzi is the first and only anti-tissue factor pathway inhibitor (anti-TFPI) approved in the U.S. for hemophilia A or B and the first hemophilia medicine approved in the U.S. to be administered via

  7. Prothrombin complex concentrate - Wikipedia

    en.wikipedia.org/wiki/Prothrombin_complex...

    It is used to treat and prevent bleeding in hemophilia B if pure factor IX is not available. [9] [11] It may also be used for reversal of warfarin therapy. [11] It is given by slow injection into a vein. [9] Another product, activated prothrombin complex concentrate or FEIBA (Factor Eight Inhibitor Bypassing Agent), may be used for acquired ...

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