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A human chimera is a human with a subset of cells with a distinct genotype than other cells, that is, having genetic chimerism.In contrast, an individual where each cell contains genetic material from a human and an animal is called a human–animal hybrid, while an organism that contains a mixture of human and non-human cells would be a human-animal chimera.
According to Greek mythology, [1] the Chimera, Chimaera, Chimæra, or Khimaira (/ k aɪ ˈ m ɪər ə, k ɪ-/ ky-MEER-ə, kih-; Ancient Greek: Χίμαιρα, romanized: Chímaira, lit. 'she-goat') [ 2 ] was a monstrous fire-breathing hybrid creature from Lycia , Asia Minor , composed of different animal parts.
A genetic chimerism or chimera (/ k aɪ ˈ m ɪər ə / ky-MEER-ə or / k ɪ ˈ m ɪər ə / kim-EER-ə) is a single organism composed of cells with more than one distinct genotype. Animal chimeras can be produced by the fusion of two (or more) embryos .
Diagnosing a chimera or mosaic is particularly difficult due to the random distribution of 46,XX and 46,XY cells within the body. In a chimeric, an organ might be made up of a mix of 46,XX and 46,XY, but is made up entirely only one genotype. When that is the case, no abnormalities are noted and other types of tissues need to be analyzed. [15]
Chimera, Chimaera, or Chimaira (Greek for "she-goat") originally referred to: Chimera (mythology) , a fire-breathing monster of ancient Lycia said to combine parts from multiple animals Mount Chimaera , a fire-spewing region of Lycia or Cilicia typically considered the inspiration for the myth
Chimera is referenced when describing the shape-shifting guardian creature that follows and protects John Smith in the movie I Am Number Four.; The character Beast from Disney's Beauty and the Beast is a Chimera-like creature, with the horns of a bison, brows of a gorilla, nose and mane of a lion, the back mane of a hyena, the tusks of a boar, the arms and chest of a bear and the hind legs and ...
The teams behind the five hair and makeup Oscar nominees take us inside the looks of 'A Different Man,' 'Emilia Pérez,' 'Nosferatu,' 'The Substance' and 'Wicked.'
In 1944, M. L. Belgovskii proposed that mosaicism could not account for certain mosaic expressions caused by chromosomal rearrangements involving heterochromatic inert regions. The associated weakening of biochemical activity led to what he called a genetic chimera. [6]