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Chloroquine (CQ) then becomes protonated (to CQ 2+), as the digestive vacuole is known to be acidic (pH 4.7); chloroquine then cannot leave by diffusion. Chloroquine caps hemozoin molecules to prevent further biocrystallization of heme, thus leading to heme buildup. Chloroquine binds to heme (or FP) to form the FP-chloroquine complex; this ...
Perianal cellulitis, also known as perianitis or perianal streptococcal dermatitis, is a bacterial infection affecting the lower layers of the skin around the anus. [1] [2] [3] It presents as bright redness in the skin and can be accompanied by pain, difficulty defecating, itching, and bleeding.
Bacteria reproduce rapidly if conditions are right for growth. Most bacteria grow best in dark, warm, moist environments with food. When grown on solid media, some bacteria form colonies as they multiply, and they may grow large enough to be seen. By growing and counting colonies of fecal coliform bacteria from a sample of water, the amount of ...
A secondary bacterial infection may be present. Syphilis (syphilitic proctitis) The symptoms are similar to other causes of infectious proctitis; rectal pain, discharge, and spasms during bowel movements, but some people may have no symptoms. Syphilis occurs in three stages.
Arcanobacterium (/ ɑːr ˈ k eɪ n oʊ b æ k ˌ t ɪər i ə m /) is a genus of bacteria. They are gram-positive, [1] non–acid fast, [1] nonmotile, [1] facultatively anaerobic, [1] and non–endospore forming. [1] They are widely distributed in nature in the microbiota of animals (including the human microbiota) and are mostly innocuous.
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The condition is usually caused by Gram-positive enteric commensal bacteria of the gut (). Clostridioides difficile is a species of Gram-positive bacteria that commonly causes severe diarrhea and other intestinal diseases when competing bacteria are wiped out by antibiotics, causing pseudomembranous colitis, whereas Clostridium septicum is responsible for most cases of neutropenic enterocolitis.
Other stool tests involve the detection of antibiotic resistance as to guide appropriate therapy, e.g. Clarithromycin resistance of Helicobacter pylori represents a major challenge in eradication therapy but the responsible bacterial genomic markers can be detected in stool using PCR technology and thus can guide the prescription of the ...